Randomised trial of ramipril in repaired tetralogy of Fallot and pulmonary regurgitation:the APPROPRIATE study (Ace inhibitors for Potential PRevention Of the deleterious effects of Pulmonary Regurgitation In Adults with repaired TEtralogy of Fallot)

Babu-Narayan, Sonya V; Uebing, Anselm; Davlouros, Periklis A; Kemp, Michael; Davidson, Simon; Dimopoulos, Konstantinos; Bayne, Stephanie; Pennell, Dudley J; Gibson, Derek G; Flather, Marcus; Kilner, Philip J; Li, Wei; Gatzoulis, Michael A

doi:10.1016/j.ijcard.2010.09.057

Randomised trial of ramipril in repaired tetralogy of Fallot and pulmonary regurgitation:the APPROPRIATE study (Ace inhibitors for Potential PRevention Of the deleterious effects of Pulmonary Regurgitation In Adults with repaired TEtralogy of Fallot)

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Babu-Narayan, Sonya V, Uebing, Anselm, Davlouros, Periklis A, Kemp, Michael, Davidson, Simon, Dimopoulos, Konstantinos, Bayne, Stephanie, Pennell, Dudley J, Gibson, Derek G, Flather, Marcus, Kilner, Philip J, Li, Wei and Gatzoulis, Michael A (2012) Randomised trial of ramipril in repaired tetralogy of Fallot and pulmonary regurgitation:the APPROPRIATE study (Ace inhibitors for Potential PRevention Of the deleterious effects of Pulmonary Regurgitation In Adults with repaired TEtralogy of Fallot). International Journal of Cardiology, 154 (3). pp. 299-305. ISSN 1874-1754

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Abstract

Optimal treatment for stable repaired tetralogy of Fallot (rTOF) patients with pulmonary regurgitation (PR) and related right ventricular (RV) dilatation, including timing of valve implantation, remains uncertain. We sought to study tolerability of the angiotensin-converting-enzyme (ACE) inhibitor ramipril and its effects on cardiovascular function in these patients.

Item Type:	Article
Additional Information:	Copyright © 2010. Published by Elsevier Ireland Ltd.
Uncontrolled Keywords:	angiotensin-converting enzyme inhibitors,double-blind method,feasibility studies,humans,prospective studies,pulmonary valve insufficiency,ramipril,tetralogy of fallot,time factors,ventricular function
Faculty \ School:	Faculty of Medicine and Health Sciences > Norwich Medical School
UEA Research Groups:	Faculty of Medicine and Health Sciences > Research Groups > Cardiovascular and Metabolic Health Faculty of Medicine and Health Sciences > Research Groups > Norwich Clinical Trials Unit Faculty of Medicine and Health Sciences > Research Groups > Public Health and Health Services Research (former - to 2023) Faculty of Medicine and Health Sciences > Research Centres > Metabolic Health
Depositing User:	Pure Connector
Date Deposited:	20 Jan 2014 16:12
Last Modified:	26 Sep 2026 07:14
URI:	https://uea-test-2026.eprints-hosting.org/id/eprint/46244
DOI:	10.1016/j.ijcard.2010.09.057

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